Agwanda is a blob of water who has control over all forms of water, including tears and dew drops. She guards the Shrine's Water of Life, and suspects Zelda has come to steal it. She is protected by three servants, the Kelpies, which must be defeated in order to reach the room that Agwanda lurks.
Agwanda attacks by quickly moving around the room, and by shooting bubbles in every direction that spread out across the room. Running into Aqwanda will greatly harm Zelda, causing her two and a half Hearts-worth of damage, whereas the bubbles will only inflict one and a half Hearts of damage. Agwanda's movement is rapid and sporadic, making her difficult to dodge. A safe spot exists in the upper-left corner of the boss room, where Agwanda will not run into Zelda.
Agwanda is fought a second time in the Vision Henge when Ganon summons the Shrine Keepers to fight Zelda on her way to the final showdown. Agwanda is fought in a similar manner as before, only now she is much weaker. Zelda however must be more careful during this fight, as the safe spot from before is not present in the room Agwanda is fought in.
- Agwanda is voiced by a male and female team with their voices overlapping each other to create a distorted effect.
- "I am Agwanda, and this is my realm! I control the waters of life and renewal. I will dry up even your tears, little one!" — Agwanda (Zelda's Adventure)
- "I am Agwanda! I dam up the streams, I draw the water underground, I gather up even the droplets of dew and deny them to my enemies. You are trespassing here!" — Agwanda (Zelda's Adventure)
- "I know you've come to steal the Water of Life! You shall not have it while I have substance to fill my form. Begone!" — Agwanda (Zelda's Adventure)